DARMIS-2018

International multicenter prospective surveillance study of antimicrobial resistance of uropathogens causing community-acquired UTI in different subsets of patients (DARMIS-2018)

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Organizers

  • Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC)
  • Russian Society of Urologists

The data are presented on antibiotic resistance of community-acquired uropathogens isolated from midstream urine samples of:

  • adults with symptomatic UTI (cystitis, pyelonephritis)
  • children and adolescents under 18 years with symptomatic UTI (cystitis, pyelonephritis)
  • pregnant women with symptomatic UTI (cystitis and pyelonephritis) and asymptomatic bacteriuria

The study design is similar to that of the DARMIS study (2010-2011)

Time period of sample collection

01 Jan 2017 - 31 Dec 2018

Geographic location of centers

34 centers, 26 cities

  • Russia: Bratsk, Voronezh, Yekaterinburg, Irkutsk, Yoshkar-Ola, Kazan, Kirov, Krasnodar, Nizhnevartovsk, Novokuznetsk, Novosibirsk, Omsk, Rostov-on-Don, Samara, St. Petersburg, Seversk, Smolensk, Surgut, Tolyatti, Tomsk, Ulyanovsk, Chelyabinsk, Yakutsk, Yaroslavl
  • Belarus: Gomel
  • Kazakhstan: Karaganda

Antibiotic susceptibility testing

Determination of minimum inhibitory concentrations (MICs) by reference broth microdillution method (BMD) in Mueller-Hinton broth (according to ISO 20776-1:2006) at the central laboratory of the Institute of Antimicrobial Chemotherapy (IAC), Smolensk State Mediacal University (SSMU)

Interpretation of MICs

Clinical susceptibility categories were assigned based on the European Committee on Antimicrobial Susceptibility Testing (EUCAST) MIC Clinical breakpoints v.10.0 (http://www.eucast.org/clinical_breakpoints/)

Study Group

  • Amineva P.G. (Yekaterinburg)
  • Becker G.G. (Novosibirsk)
  • Bulkin A.N. (St. Petersburg)
  • Bykonya S.A. (Tomsk)
  • Chastoedova A.N. (Kirov)
  • Domanskaya O.V. (Novokuznetsk)
  • Elokhina E.V. (Omsk)
  • Ershova M.G. (Yaroslavl)
  • Ivanova I.A. (Yoshkar-Ola)
  • Khaidarshina N.E. (Chelyabinsk)
  • Khusnutdinova T.A. (St. Petersburg)
  • Kogan M.I. (Rostov-on-Don)
  • Kulchavenya E.V. (Novosibirsk)
  • Lavrinenko A.V. (Kazakhstan)
  • Lyamin A.V. (Samara)
  • Malev I.V. (Smolensk)
  • Malyavin A.I. (Ulyanovsk)
  • Martyanova N.M. (Tolyatti)
  • Moskvitina E.N. (Seversk)
  • Mutin M.Yu. (Bratsk)
  • Naboka Yu.L. (Rostov-on-Don)
  • Nikiforovskaya N.N. (Smolensk)
  • Palagin I.S. (Smolensk)
  • Plugin P.S. (Novosibirsk)
  • Popova L.D. (Omsk)
  • Portnyagina U.S. (Yakutsk)
  • Shamaeva S.Kh. (Yakutsk)
  • Shipitsyna E.V. (St. Petersburg)
  • Shirokova T.M. (Kirov)
  • Sidorova R.K. (Ulyanovsk)
  • Strebkova V.V. (Voronezh)
  • Sukhoreva M.V. (Irkutsk)
  • Tapalsky D.V. (Belarus)
  • Valiullina I.R. (Kazan)
  • Varganova A.N. (Surgut)
  • Varibrus E.V. (Krasnodar)
  • Vasilyeva I.R. (Nizhnevartovsk)
  • Vetokhina A.V. (Irkutsk)
  • Volkovskaya I.V. (Tomsk)
  • Zhestkov A.V. (Samara)

Coordinator

Ivan S. Palagin

Research fellow

Institute of Antimicrobial Chemotherapy (IAC),
Smolensk State Medical University (SSMU)

ivan.palagin@gmail.com

Institute of Antimicrobial Chemotherapy
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