Epidemiological study “SPECTRUM”

The prevalence and antimicrobial susceptibility of circulating S. pneumoniae serotypes in adult population in Russia

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Study Objective

To estimate prevalence and antimicrobial susceptibility of circulated S. pneumoniae serotypes in adult population in different regions of the Russian Federation.

Dataset

  • Bacterial isolates: 500
  • S. pneumoniae: 500
  • Time: June 01, 2019 - January 15, 2020
  • Participating centers: 29 hospitals in 20 cities of Russian Federation

Inclusion Criteria

Isolates of S. pneumoniae obtained from patients with invasive pneumococcal disease (IPD), community-acquired pneumonia (CAP), sinusitis/acute otitis media (AOM) and healthy carriers.

Study Procedures

Re-identification, typing using real-time PCR with 27 primer pairs and antimicrobial susceptibility testing were performed in the central laboratory by standardized methods.

Study Coordinator

Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy IACMAC

Study Sponsor

MSD Sharp & Dohme Corp

Study Group «SPECTRUM»

  • Tsvetkova I.A. (St. Petersburg),
  • Morozova O.A. (Moscow),
  • Kirillova G.Sh. (Kazan),
  • Popova L.D. (Omsk)
  • Moskvitina E.N. (Seversk)
  • Petrova T.A. (Smolensk),
  • Martyanova N.M. (Tolyatti)
  • Ershova M.G. (Yaroslavl)
  • Bykonya S.A. (Tomsk).

Publications

  1. Kozlov R.S., Muraviov A.A., Chagaryan A.N., Ivanchik N.V., Kurkova A.A., Kuzmenkov A.Yu., Trushin I.V., Sukhorukova M.V. and «SPECTRUM» Study Group. The prevalence and antimicrobial susceptibility of circulating S. pneumoniae serotypes in adult population in Russia (epidemiological study «SPECTRUM»). Clinical Microbiology and Antimicrobial Chemotherapy. 2021; 23(2):127-137.
    10.36488/cmac.2021.2.127-137
  2. Muraviov A.A., Chagaryan A.N., Ivanchik N.V., Kurkova A.A., Tsvetkova I.A., Kozlov R.S. and «SPECTRUM» Study Group. The prevalence of circulating S. pneumoniae serotypes in people older than 18 years: healthy carriers, patients with acute otitis media, community-acquired pneumonia, and invasive pneumococcal infections (epidemiological study «SPECTRUM»). Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(4):275-281.
    10.36488/cmac.2019.4.275-281